Hyderabad (Telangana) [India], June 3: Infertility affects millions of couples worldwide, and while in vitro fertilization (IVF) has provided hope, success rates have traditionally varied. Many couples face multiple IVF cycles before achieving a successful pregnancy. However, with the advancements in Artificial Intelligence (AI) and Preimplantation Genetic Testing (PGT), fertility treatments are becoming more precise, leading to higher IVF success rates and healthier pregnancies.

Dr. S. Vyjayanthi, a leading Fertility Specialist and Director of MotherToBe Fertility Centre, discusses how these groundbreaking innovations are transforming the field of reproductive medicine.

The Role of AI in IVF Treatments

Artificial Intelligence is revolutionizing IVF by improving accuracy in embryo selection, ovarian stimulation monitoring, and sperm analysis.

AI in Embryo Selection

One of the most critical steps in IVF is choosing the healthiest embryo for implantation. Traditionally, embryologists assess embryos visually under a microscope, relying on subjective judgment. AI enhances this process by:

• Analyzing thousands of embryo images to detect subtle differences that the human eye might miss

• Predicting embryo viability based on morphology, developmental patterns, and genetic health

• Reducing implantation failures by selecting the embryos with the highest potential for successful pregnancy

AI-powered systems use machine learning algorithms trained on large datasets of embryo images. These systems assign an embryo grading score, helping embryologists choose the embryo with the highest implantation potential.

AI in Ovarian Stimulation Monitoring

Before egg retrieval, ovarian stimulation is required to encourage the growth of multiple follicles. However, the right dosage of medications is crucial to prevent complications such as Ovarian Hyperstimulation Syndrome (OHSS). AI plays a key role by:

• Monitoring hormone levels and follicular growth to predict the optimal trigger time

• Personalizing medication doses based on real-time patient data, ensuring safer and more effective ovarian stimulation

• Reducing medication side effects and improving egg retrieval outcomes

AI in Sperm Analysis

Male factor infertility contributes to nearly 50 percent of infertility cases. Traditional sperm analysis relies on manual assessments, but AI-powered sperm analysis offers:

• More precise evaluation of sperm motility, morphology, and concentration

• Enhanced selection of high-quality sperm for fertilization in IVF or ICSI (Intracytoplasmic Sperm Injection)

• A better understanding of sperm DNA fragmentation, which can impact embryo development

AI-driven sperm selection allows fertility specialists to make informed decisions, maximizing the chances of conception.

Preimplantation Genetic Testing (PGT) in IVF

Preimplantation Genetic Testing (PGT) is transforming IVF success rates by ensuring genetically normal embryos are selected for transfer.

Types of PGT and Their Role in IVF

• PGT-A (Aneuploidy Screening): Screens embryos for chromosomal abnormalities, such as Down syndrome and Turner syndrome. This reduces the risk of implantation failure and miscarriage.

• PGT-M (Monogenic Disorders): Screens for inherited single-gene disorders, such as Cystic Fibrosis and Sickle Cell Anemia, helping parents with genetic conditions have healthy children.

• PGT-SR (Structural Rearrangements): Identifies chromosomal translocations that may cause recurrent miscarriages or failed implantation.

During IVF, a few cells from a developing embryo are biopsied and tested before implantation. This ensures that only genetically normal embryos are transferred, improving pregnancy outcomes and reducing the risk of miscarriage.

How AI and PGT Are Increasing IVF Success Rates

The combination of AI-powered embryo selection and Preimplantation Genetic Testing (PGT) has significantly improved IVF success rates by:

• Improving embryo quality and selection accuracy

• Reducing IVF failure rates and miscarriages

• Enhancing personalized treatment approaches

• Minimizing the risks of multiple pregnancies by supporting elective single embryo transfer (eSET)

According to Dr. Vyjayanthi, “The integration of AI in embryo selection and PGT has transformed the success rates of IVF, making treatments more precise, personalized, and patient-friendly. At MotherToBe, we combine the latest AI-driven tools with genetic testing to maximize success rates and offer couples a better chance of achieving parenthood.”

Who Can Benefit from AI and PGT in IVF?

These technologies are particularly beneficial for:

• Women over 35 years of age experiencing low ovarian reserve

• Couples with a history of multiple failed IVF cycles

• Women with recurrent pregnancy loss

• Couples with a known genetic disorder (e.g., Thalassemia, BRCA mutation)

• Male infertility cases requiring advanced sperm selection techniques

At MotherToBe Fertility Centre, AI-powered embryo selection and PGT are used to enhance precision and improve IVF success rates.

Future of AI and Genetic Testing in Fertility Treatments

The future of fertility treatments looks promising, with continuous advancements such as:

• AI-powered embryo culture monitoring using time-lapse imaging

• Advanced sperm sorting techniques using AI-driven microfluidic chips

• Non-invasive genetic screening (NIPGS), eliminating the need for embryo biopsy

With ongoing research and technological advancements, AI and genetic testing will continue to enhance reproductive medicine, offering new hope to couples worldwide.

The integration of Artificial Intelligence and Preimplantation Genetic Testing (PGT) is revolutionizing IVF treatments, improving success rates, and reducing genetic risks.

For those struggling with infertility, these cutting-edge advancements provide a path to parenthood with greater accuracy and confidence.

If you are considering IVF, consult with Dr. Vyjayanthi at MotherToBe Fertility Centre, a leader in AI-assisted fertility treatments and PGT-based embryo selection.

For consultations and advanced fertility treatments, visit MotherToBe Fertility Centre in Hyderabad.